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| WEB-THERMODYN: Sequence analysis software for profiling DNA helical stability. | ||
| Yanlin Huang and David Kowalski | ||
| Nucleic Acids Res (2003), 31(13):3819-21 | ||
| WEB-THERMODYN analyzes DNA sequences and computes the DNA helical stability, i.e. the free energy required to unwind and separate the strands of the double helix. A helical stability profile across a selected DNA region or the entire sequence is generated by sliding-window analysis. WEB-THERMODYN can predict sites of low helical stability present at regulatory regions for transcription and replication and can be used to test the influence of mutations. The program can beaccessed at: http://wings.buffalo.edu/gsa/dna/dk/WEBTHERMODYN/. | ||
OriDB annotation of this paper: |
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Origin site(s) analysed by ARS assay: |
None curated. | |
Origin site(s) analysed by 2D gel analysis: |
None curated. | |
Predicted ACS element: |
None curated. | |
Experimentally confirmed ACS element: |
None curated. | |
Activation ('firing') time determined: |
None curated. | |
Activation ('firing') efficiency determined: |
None curated. | |
Analysed by microarray: |
None curated. | |
Other analysis: |
None curated. | |
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