The Saccharomyces Genome Database (SGD) are in the process of adding the confirmed replication origin sites (ARS) shown in OriDB. The putative replication origin sites described in OriDB will only be added to SGD once they have been confirmed. As SGD includes the addition origin sites they will include links to the appropriate OriDB record.

Only confirmed replication origins have been named - this is Saccharomyces Genome Database (SGD) standard practice. Putative replication origins can conveniently be referred to either by a location based name (such as ARS at II-774 to refer to the origin 774 kb from the left end of chromosome II) or where available a proposed ARS name (proARS; e.g. proARS227).

OriDB web pages can be viewed through any web browser. We have tested the pages on Safari (Mac OS X) and Firefox (Windows) and have sucessfully viewed them with other browsers, such as Explorer (Mac OS X and Windows). Many of the pages use Javascript and all of the graphics are Flash generated. If necessary, you can update the version of Adobe Flash on your computer from here.

The phylogenetic sequence conservation tab will only display data if it has been reported for that origin site. This tab provides a summary of the reported phylogenetic sequence conservation of Origin Sequence Elements and where available an appropriate alignment. The link to the UCSC Genome Browser on the Origin Summary Information tab of every origin record can also be used to display available phylogenetic sequence conservation.

Please note that we are in the process of including additional alignments and these are presently available for the following origin sites: ARS106 ; ARS107 ; ARS201.5 ; ARS202 ; ARS207 ; ARS208 ; ARS209 ; ARS211 ; ARS214 ; ARS215 ; ARS225 ; ARS305 ; ARS306 ; ARS307 ; ARS309 ; ARS310 ; ARS313 ; ARS314 ; ARS316 ; ARS319 ; ARS405 ; ARS409 ; ARS414 ; ARS422 ; ARS431 ; ARS432 ; ARS432.5 ; ARS434 ; ARS507 ; ARS508 ; ARS510 ; ARS512 ; ARS514 ; ARS518 ; ARS606 ; ARS607 ; ARS608 ; ARS609 ; ARS702 ; ARS710 ; ARS716 ; ARS717 ; ARS720 ; ARS722 ; ARS731 ; ARS805 ; ARS913 ; ARS913.5 ; ARS914 ; ARS1020 ; ARS1104.5 ; ARS1106 ; ARS1106.3 ; ARS1118 ; ARS1211 ; ARS1213 ; ARS1216.5 ; ARS1220 ; ARS1234 ; ARS1305 ; ARS1307 ; ARS1324 ; ARS1330 ; ARS1415 ; ARS1419 ; ARS1420 ; ARS1507 ; ARS1529 ; ARS1619 ; ARS1622 ; ARS1623 ;

What reference should I use to refer to the OriDB database?
The 2007 Nucleic Acids Research Database Issue includes a paper describing OriDB. This paper can be used as a reference for OriDB as a database.

How should I cite data found in OriDB?
OriDB is a collation of previously published data and at present does not include any unpublished results. Therefore you should cite the relevant original paper as shown on the Reference for this Origin tab page for each Origin Site.

Probably! Please contact us with additional data that you would like us to include in OriDB. We will give priority to genome-wide datasets, but will also include data relevant to individual origins where appropriate. If you have a large dataset that you would like to be available at the time of publication please contact us with as much advanced notice as possible.

At present OriDB only includes published datasets. This ensures that all work has undergone peer review and saves us from having to make difficult calls as to which datasets warrant inclusion. However, we understand that there are high quality, unpublished datasets that would be of interest to OriDB users. Therefore, in the long term we may include a limited number of unpublished datasets where we feel there is good justification for doing so. Any such datasets will be clearly indicated.

At present OriDB is limited to the budding yeast, S. cerevisiae. In the long term we would be interested in including other model systems as more data becomes available. If you have genome-wide DNA replication origin mapping data and/or are interested in collaborating on developing OriDB for other model systems please contact us.